This technology allows one to prepare high-purity PET・SPECT probes with easy purification. The composite polymers containing isotope labeled precursors and phase-transfer catalysts enable efficient installation of radioactive element and are easily separated from labeled products.
Presentation of structurally constrained peptides is achieved by integration of peptides into fluorescent protein. Target-binding peptide with high affinity and avidity is rapidly screened by the technology.
We proposed and demonstrated the single-cell isolation of bacteria using a microenclosure array with a structure composed of many micropillars. We fabricated the microenclosure array on a semiconductor wafer by electron beam lithography and the dry etching technique. The capturing frequency for single cells of Escherichia coli was approximately 50% using a 4-mm-width microenclosure array. We think that the proposed novel technique is very simple and useful for the single-cell isolation of many kinds of bacteria using a microenclosure array of optimum size.
We developed a method to biosynthesize 3-hydroxy-4-methylvalerate (3H4MV)-containing bacterial polyester, which shows improved long-term stability and processability than other known bacterial polyesters, by expressing leucine metabolism-related enzymes derived from Clostridium difficile in recombinant Escherichia coli.
A new-type air-cell composed of a metallic sodium as a cathode and a sodium ion conducting ceramics as a sepalator has been developed. This configulation enable us to incorporate aqueous electrolyte in an anode compartment. Theoretical energy density exceeds 1000 Wh/kg. High power density is available owing to excellent ionic conducivities in sodium-besed electrolytes. Rechargeability is now under investigation.
A liquid-liquid countercurrent centrifugal extractor with Taylor vortices was developed. The high-performance extraction with multiple theoretical stages was attained successfully by a single extractor.
A simple device that is composed of three elastic tubes that are twisted or braided and inflated by turns can propel inside a pipe quickly. It is structurally simple and pliable, therefore it can move a thin and bent pipe. This mechanism can be used for a endoscope.
Novel liquid optical device is proposed for various laser applications. By applying the device to the existing processing / measurement lasers, it can transform the Gaussian laser beam profile to the quasi-flat top, annular or Bessel beams for totally new applications.